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Prevention of Hepatitis C Virus (HCV) and HIV-1 Co-Infections

A collaborative project financed by the EC Framework Programme 7

PEACHI-03 Clinical Trial Update


Following the completion of Work Package 1 (Production of clinical lots and approval for use in clinical trials), work has begun on PEACHI-03 (safety and immunogenicity of second generation viral vectored technology using ChAd3 and MVA, employing NSmut linked to the human MHC class II invariant chain, in both healthy subjects and HIV-positive patients).


The protocol for the healthy volunteer and DAA-treated patient arms has been completed and currently is under review by the relevant UK regulatory bodies.   Recruitment is scheduled to begin in September 2017.


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The goal of the PEACHI project is to develop simple, affordable and effective vaccine strategies that can be given alone or in combination to prevent hepatitis C virus (HCV), human immunodeficiency virus type 1 (HIV-1) and co-infection.


The vaccines are based on novel and powerful viral vectors for in vivo delivery of antigens. Read more about the project here... 


This goal requires a multidisciplinary approach in which diverse expertise and technologies converge.


PEACHI is a unique consortium that consists of cutting edge clinical and scientific expertise, partnered with industry. In the last two years partnership members have employed viral vectored technology to develop the most immunogenic HIV-1 and HCV vaccines described to date.

If you have any questions regarding PEACHI please contact the team at the following email address: